This is expressed through a study of cell culture and animal experiments conducted by various Ku Leuven laboratories. Their findings were published in Molecular Cancer Therapeutics, a journal of the Keep Calm My God Is Stronger Than Stomach Cancer Humor hot Shirt American Society.
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New research suggests antidepressant sertraline helps inhibit the growth of cancer cells. This substance acts on a metabolism addiction that allows different types of cancers to develop.
This is expressed through a study of cell culture and animal experiments conducted by various Ku Leuven laboratories. Their findings were published in Molecular Cancer Therapeutics, a journal of the Keep Calm My God Is Stronger Than Stomach Cancer Humor hot Shirt American Society for Cancer Research.
Cancer cells use different biological mechanisms to stimulate their growth. In some types of breast cancer, leukemia, skin cancer, brain tumors, and lung cancer, among others, malignant cells produce a large amount of serine and glycine, two amino acids. This product stimulates the growth of cancer cells to the point that they become addicted to serine and glycine.
“This mechanism is an interesting target because cancer cells are very dependent on it,” said Professor Kim De Keersmaecker, head of the Cancer Disease Mechanism Laboratory (LDMC).
“Healthy cells use this mechanism to a lesser extent and also absorb serine and glycine from food. However, this is not enough for cancer cells, which means that they begin to produce more. If we can stop this production, we will be able to fight Keersmaecker cancer for more.
The examination showed that antidepressant sertraline was the most effective substance. Researchers Shauni Geeraerts (LDMC and CMPG) and Kim Kampen (LDMC) mentioned: “Other studies have shown that sertraline has a certain anti-cancer activity, but there is no explanation for this.
“In this study, we were able to demonstrate that sertraline inhibits the Keep Calm My God Is Stronger Than Stomach Cancer Humor hot Shirt production of serine and glycine, which reduces the growth of cancer cells. We also found that this substance is most effective when combined with other therapeutic substances. In studies on mice, we found that sertraline combined with another therapy strongly inhibits the growth of breast cancer cells. ”
“Now that we have been able to identify this mechanism of breast cancer, we can start examining other types of cancer that are also addicted to serine and glycine a combination,” said Professor De Keersmaecker. “This is as is the case with T-cell leukemia, as well as in some types of brain, lung, and skin cancers. The more sertraline-sensitive tumors we identify, the more prospects we have of helping patients in the future.
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